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Frame (Overo)
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One copy usually produces "jagged" white markings on sides
of body and face, "framed" by color on the back, belly and
legs.
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A horse may carry this gene without it causing any white.
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The white tends to look "spray painted" on, with jagged
edges.
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Two copies (HOMOzygous) produces "lethal white", a
white foal with an unfinished (no exit), non-motile intestinal
tract, and other epithelial cell problems.
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When breeding white-spotted horses, or horses that have
white spotting (especially frame) in their pedigree, they should
always be tested to assure that two LWO carriers are not mated.
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